Monthly B12 Program

2000mcg/mL vial (Methylcobalamin)
$120/month flat rate
  • Enhance Energy, Reduce Fatigue[1]
  • Lower Stress Levels[2]
  • Improve Mood & Mental Wellbeing[3]
  • Improve Mental Clarity, Reduce Brain Fog[4]
The B12 Program includes a monthly supply of Methylcobalamin B12, plus sterile injection kit. 2000mcg/mL x 5ml Vial.

Enov.one provides service to 47/50 of the United States. Currently enov.one does not serve: NM, MS, LA. All other states are within our service area.

Free shipping if approved
Convenient Process
FDA-regulated pharmacies
In stock & ready to ship

B12 Program

2000mcg/mL Vial (Methylcobalamin)

$120
monthly flat rate
Free shipping if approved
Convenient Process
FDA-regulated pharmacies
In stock, ready to ship
  • Enhance Energy, Reduce Fatigue[1]
  • Lower Stress Levels[2]
  • Improve Mood & Mental Wellbeing[3]
  • Improve Mental Clarity, Reduce Brain Fog[4]
The B12 Program includes a monthly supply of Methylcobalamin B12, plus sterile injection kit. 2000mcg/mL x 5ml Vial.
Enov.one currently services all 50 of the United States. We have your back anywhere in the US!

How We Compare

Our pricing compared to others providing services for NAD+ Injections

Enov.one Vine Rx LivelongRx Gents
$120 $135 $149 $195

Feel More
Energetic[1]

Reduce Stress
Levels[2]

Support Mental
Wellbeing[3]

Reduce Brain
Fog[4]

What could b12 injections do for you?

Some of our patients experience life changing results. See for yourself!

Methylcobalamin is one of the active forms of Vitamin B12, an essential nutrient that plays a critical role in many bodily functions due to its role in various metabolic processes.
Energy Production: Vitamin B12 is essential for converting food into glucose, which the body uses for energy. Mood Regulation and Brain Health: B12 contributes to the synthesis of neurotransmitters that support brain health. Nerve Health, by supporting the maintenance of the protective layer around nerves Red Blood Cell production, preventing anemia DNA Synthesis and repair, working closely with folate (vitamin B9) in the synthesis of DNA and RNA- essential for the growth and function of all cells in the body. (See references below)
Research has demonstrated intramuscular B12 injections to be superior to B12 capsules or sublingual droppers. Furthermore, many individuals carry SNPs that significantly limit the oral and cellular absorption of B12, making IM injections the most ideal route of administration.
Cyanocobalamin has a cyanide on the vitamin instead of a methyl group. Simply put, it is inactive and can even be detrimental. Though we can activate a small proportion of it, it can actually replace natural stores of B12 with inactive B12, though it will show on blood labs as if it has normalized B12 levels.

Absolutely, administering both injections on the same day is generally safe. However, for those new to this, it might be wise to alternate days for each injection initially to monitor your body’s reaction. 

Depending on dosage, some people feel immediate and drastic results- the moment the B12 begins infusing, you might feel a veil lifting alongside instant clarity. Others need a couple of weeks for results to kick in.

Intramuscular B12 injections can help those experiencing fatigue, sleep, mood or energy issues, as well as anxiety. They work by supporting the body’s methylation pathways.

On a molecular level, methylation is a process by which a methyl group (CH3) is added to a molecule, often DNA, affecting gene expression and cell function. It’s an elemental biochemical reaction involved in many cellular processes across multiple biological pathways in the body- each shaping different aspects of our health.

Methylation can profoundly impact the production and regulation of neurotransmitters, which play critical roles in mood, cognition, and overall brain function. Impaired methylation can lead to inefficient detoxification, with implications such as oxidative stress or inflammation. It also has a profound impact on fat metabolism through its regulation of gene expression, as well as its influence on enzymes that process fats in their synthesis, breakdown, and storage.

Why methylcobalamin over cyanocobalamin or B12 capsules? Cyanocobalamin has a cyanide on the vitamin instead of a methyl group. Simply put, it is inactive and can even be detrimental. Though we can activate a small proportion of it, it can actually replace natural stores of B12 with inactive B12, though it will show on blood labs as if it has normalized B12 levels. 

Research has demonstrated intramuscular B12 injections to be superior to B12 capsules or sublingual droppers. Furthermore, many individuals carry SNPs that significantly limit the oral and cellular absorption of B12, making IM injections the most ideal route of administration.

Morales-Gutierrez J, Díaz-Cortés S, Montoya-Giraldo MA, Zuluaga AF. Toxicity induced by multiple high doses of vitamin B12 during pernicious anemia treatment: a case report. Clin Toxicol (Phila). 2020 Feb;58(2):129-131. doi: 10.1080/15563650.2019.1606432. Epub 2019 Apr 24. PMID: 31018715.;

How it works

Complete our quick and convenient three-step process.

1

5-minute medical intake

Answer a simple 5 minute intake on your phone or any other device from the comfort of your living room. 

2

Free shipping & Doctor review

Your medical history and intake are reviewed by medical professional and meds are shipped via an FDA-regulated 503a US-based pharmacy if deemed medically appropriate.

3

Ongoing &
Free support

Our dedicated care team is available 24/7 via our HIPAA compliant messaging system or by phone.

Ignite your energy

Start your plan today

Monthly B12 Program

2000mcg/mL vial (Methylcobalamin)

$120/month

  • 1 5mL vial with 10000mcg of B12
  • Methylcobalamin (NOT cyanocobalamin)
  • Sterile kit included
  • Compounded by US Pharmacy
  • Lab-tested
  • Free shipping
Start today with a 5 minute intake.

Products that require a prescription will need you to have an online meeting with a qualified healthcare professional, who will determine if a prescription is appropriate for you. Important safety information can be found further below. The benefits described on enov.one are based on research conducted by independent third parties. This medication is offered through a subscription model, which you can cancel at any time. Please note that the product's actual packaging may differ from the images shown. After a healthcare professional's evaluation, expect a processing and shipping time of 3-5 days.

The Enovone Promise

Enovone goes above and beyond to deliver an excellent experience.

Top Quality
medications

FDA regulated 503A compound pharmacy. Our compounds are safe, pure, and made in America.

Convenience Without Compromise

Highest quality standards, lowest price. Easy to use and convenient onboarding process. Medical intake on any device.

24/7 Support
Included

Communicate easily and conveniently with your provider and get answers to any questions you may have, all from your HIPAA-compliant portal.

HEAR FROM SATISFIED CUSTOMERS

Frequently Asked Questions (FAQs)

Begin by taking our short online assessment. Based on your responses, we’ll determine if you’re eligible for our services and connect you with one of our board-certified doctors for validation, all from the comfort of your home.

All our partner pharmacies are 503A FDA regulated US based pharmacies. There are routine inspections for quality, efficacy, potency, and safety. If approved medications are shipped directly to you in discreet packaging, ensuring privacy and convenience, unless requested otherwise. Shipping is fast and free.

No insurance is required. We offer transparent, out-of-pocket pricing for all our services, including medications, and ongoing care. Ask our care team if your HSA plan applies.

Our services are designed to address a wide range of conditions related to longevity, including fatigue, anxiety, brain fog, mood imbalances, and weight management. Our medical team will evaluate your specific needs and determine the most appropriate treatment plan.

Absolutely. Our care team is always on hand to provide support, answer questions, and help you navigate your health journey. Regular check-ins and adjustments to your treatment plan are part of our commitment to your well-being.

In emergencies, immediately contact 911 or seek in-person care at an urgent care or Emergency Department.

Our commitment to HIPAA compliance includes stringent security measures for protecting PHI. We ensure that all digital systems involved in storing or manipulating PHI employ robust encryption both at rest and in transit, safeguarding your personal information against unauthorized access.

You can manage your subscription or orders through our customer portal. This includes pausing, canceling, or changing your order details before the next shipment is processed.

We offer flexibility in managing subscriptions and one-time purchases. While we can’t accept returns once a product has left the pharmacy, we are committed to addressing any concerns about your order to ensure satisfaction.

Enov.one provides service to 48/50 of the United States. Currently enov.one does not serve: LA, MS. All other states are within our service area.

No, Enovone offers a flat pricing guarantee. Regardless of the dosage required for your treatment plan, the price remains the same, ensuring transparency and affordability in our care.

Frequently Asked Questions (FAQs)

Begin by taking our short online assessment. Based on your responses, we’ll determine if you’re eligible for our services and connect you with one of our board-certified doctors for validation, all from the comfort of your home.

All our partner pharmacies are 503A FDA regulated US based pharmacies. There are routine inspections for quality, efficacy, potency, and safety. If approved medications are shipped directly to you in discreet packaging, ensuring privacy and convenience, unless requested otherwise. Shipping is fast and free.

No insurance is required. We offer transparent, out-of-pocket pricing for all our services, including medications, and ongoing care. Ask our care team if your HSA plan applies.

Our services are designed to address a wide range of conditions related to longevity, including fatigue, anxiety, brain fog, mood imbalances, and weight management. Our medical team will evaluate your specific needs and determine the most appropriate treatment plan.

Absolutely. Our care team is always on hand to provide support, answer questions, and help you navigate your health journey. Regular check-ins and adjustments to your treatment plan are part of our commitment to your well-being.

In emergencies, immediately contact 911 or seek in-person care at an urgent care or Emergency Department.

Our commitment to HIPAA compliance includes stringent security measures for protecting PHI. We ensure that all digital systems involved in storing or manipulating PHI employ robust encryption both at rest and in transit, safeguarding your personal information against unauthorized access.

You can manage your subscription or orders through our customer portal. This includes pausing, canceling, or changing your order details before the next shipment is processed.

We offer flexibility in managing subscriptions and one-time purchases. While we can’t accept returns once a product has left the pharmacy, we are committed to addressing any concerns about your order to ensure satisfaction.

Enov.one provides service to 48/50 of the United States. Currently enov.one does not serve: NM, MS. All other states are within our service area.

No, Enovone offers a flat pricing guarantee. Regardless of the dosage required for your treatment plan, the price remains the same, ensuring transparency and affordability in our care.

IMPORTANT SAFETY INFORMATION
& COMMON SIDE EFFECTS

When taken at appropriate doses, vitamin B-12 supplements are generally considered safe. While the recommended daily amount of vitamin B-12 for adults is 2.4 micrograms, higher doses have been found to be safe. Your body absorbs only as much as it needs, and any excess passes through your urine.

The primary side effect frequently observed with B12 injections is discomfort at the site of injection. Should this happen, think about altering the injection’s location on your body or decreasing the frequency of injections. B12 injections should not be utilized if you are pregnant, nursing, or if you intend to get pregnant or breastfeed in the near future. High doses of vitamin B-12, such as those used to treat a deficiency, might cause: Headache, Nausea and vomiting, Diarrhea, Fatigue or weakness, Tingling sensation in hands and feet.

Disclaimer: The statements mentioned have not undergone review by the Food and Drug Administration. This product is not designed to diagnose, remedy, cure, or avert any illness.

References:

  1. Jatoi S, Hafeez A, Riaz SU, Ali A, Ghauri MI, Zehra M. Low Vitamin B12 Levels: An Underestimated Cause Of Minimal Cognitive Impairment And Dementia. Cureus. 2020 Feb 13;12(2):e6976. doi: 10.7759/cureus.6976. PMID: 32206454; PMCID: PMC7077099.
  2. Young LM, Pipingas A, White DJ, Gauci S, Scholey A. A Systematic Review and Meta-Analysis of B Vitamin Supplementation on Depressive Symptoms, Anxiety, and Stress: Effects on Healthy and ‘At-Risk’ Individuals. Nutrients. 2019 Sep 16;11(9):2232. doi: 10.3390/nu11092232. PMID: 31527485; PMCID: PMC6770181.
  3. Coppen A, Bolander-Gouaille C. Treatment of depression: time to consider folic acid and vitamin B12. Journal of Psychopharmacology. 2005;19(1):59-65. doi:10.1177/0269881105048899
  4. Wolffenbuttel BHR, Wouters HJCM, Heiner-Fokkema MR, van der Klauw MM. The Many Faces of Cobalamin (Vitamin B12) Deficiency. Mayo Clin Proc Innov Qual Outcomes. 2019 May 27;3(2):200-214. doi: 10.1016/j.mayocpiqo.2019.03.002. PMID: 31193945; PMCID: PMC6543499.

*Should you express interest in a product requiring a prescription, Enov.one will facilitate arranging an evaluation with a certified healthcare practitioner. This professional will assess your suitability for the product. If deemed suitable, the practitioner may issue a prescription, which can be filled at one of our affiliated pharmacies unless you specify an alternative.

Everyone deserves their own health algorithm. 

Enovone, Inc.
2261 Market Street STE 5495
San Francisco, CA 94114

We serve the following geographical areas:

Enov.one provides service to 48/50 of the United States. Currently enov.one does not serve: LA, MS. All other states are within our service area.

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