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Hypomethylation Stack (Folate Subtype)

Hypomethylation Stack (Folate Subtype)

The Hypomethylation Entourage Stack Subtype Folate is a targeted blend of high-quality supplements designed to support optimal methylation processes, with a focus on folate supplementation. This stack is customized based on individual patient goals, symptoms, genetic predispositions, and diagnostic results, providing comprehensive support for your methylation cycle.

Methylation is a crucial biochemical process that involves the addition of a methyl group to DNA, proteins, and other molecules. This process is essential for numerous biological functions, including neurotransmitter synthesis, detoxification, cardiovascular health, eye health, muscle health, bone health, and redox balance. Maintaining a desirable level of homocysteine in the blood has become a leading biomarker for cardiovascular health, alongside healthy cholesterol and triglyceride levels. Preventing elevated homocysteine levels is also associated with the maintenance of bone, female reproductive, cognitive, and neurological health.

Bar Shapira, MSc
Medical Research Team
Published June 2, 2024

What Does It Do?

The Hypomethylation Entourage Stack Subtype Folate supports methylation by providing essential nutrients that facilitate this critical process. Here’s a detailed look at each supplement and its role in the stack:

  • Methyl-Guard Plus by Thorne:

      • Function: This supplement supports methylation and promotes healthy homocysteine levels with betaine (trimethylglycine), 5-MTHF (the active form of folate), riboflavin 5′-phosphate (the active form of vitamin B2), pyridoxal 5′-phosphate (the active form of vitamin B6), and methylcobalamin (an active form of vitamin B12).
      • Benefit: Providing these key nutrients supports the body’s ability to carry out methylation efficiently, helping to maintain optimal homocysteine levels and support overall metabolic health.

O.N.E.™ Multivitamin:

    • Function: This comprehensive multivitamin provides essential nutrients required for overall health, including vitamins and minerals that support methylation.
    • Benefit: Ensuring a broad spectrum of nutrient intake helps support multiple aspects of health and ensures that all co-factors needed for methylation are available.
  •  

NAC by Thorne:

    • Function: N-acetyl cysteine (NAC) supports detoxification and antioxidant activity, crucial for maintaining cellular health and aiding the methylation cycle.
    • Benefit: Supporting detoxification pathways helps reduce oxidative stress and maintain overall cellular health, which is essential for optimal methylation.

Magnesium (Glycinate) by Pure Encapsulations:

    • Function: Magnesium is essential for numerous biochemical reactions, including those involved in methylation. This form of magnesium is highly absorbable and gentle on the stomach.
    • Benefit: Providing adequate magnesium supports overall metabolic health and ensures that the body can efficiently carry out methylation processes.

Acetyl-L-Carnitine by Thorne:

    • Function: This amino acid derivative supports energy production and cognitive function, enhancing overall metabolic health and supporting methylation processes.
    • Benefit: Improving energy production and cognitive function helps support overall health and ensures that the body has the energy needed for efficient methylation.

D3 & K2 by Inwell Biosciences:

    • Function: Vitamin D3 and K2 work synergistically to support bone health, cardiovascular health, and overall immune function, which are all vital for optimal methylation.
    • Benefit: Ensuring adequate levels of these vitamins supports overall health and enhances the body’s ability to carry out methylation processes efficiently.

CoQ10 120mg by Pure Encapsulations:

    • Function: Coenzyme Q10 is a powerful antioxidant that supports cellular energy production and cardiovascular health, both important for maintaining effective methylation.
    • Benefit: Supporting cellular energy production and reducing oxidative stress helps maintain overall health and ensures efficient methylation.

B-Complex Plus by Pure Encapsulations:

    • Function: This comprehensive B-vitamin complex supports energy production, neurological health, and methylation, providing essential cofactors for the methylation cycle.
    • Benefit: Ensuring adequate intake of B vitamins supports overall health and enhances the body’s ability to carry out methylation processes efficiently.

OmegAvail TG1000 by Designs for Health:

    • Function: This high-potency omega-3 supplement supports cardiovascular health, cognitive function, and anti-inflammatory processes, which are crucial for maintaining a healthy methylation cycle.
    • Benefit: Reducing inflammation and supporting overall cardiovascular health helps maintain efficient methylation processes.

OmegAvail TG1000 by Designs for Health:

    • Function: This high-potency omega-3 supplement supports cardiovascular health, cognitive function, and anti-inflammatory processes, which are crucial for maintaining a healthy methylation cycle.
    • Benefit: Reducing inflammation and supporting overall cardiovascular health helps maintain efficient methylation processes.

What is it good for?

The Hypomethylation Entourage Stack Subtype Folate is beneficial for individuals with hypomethylation issues, supporting cardiovascular, cognitive, and overall metabolic health. By addressing the underlying causes of hypomethylation, this stack helps:

  • Maintain Optimal Homocysteine Levels: Elevated homocysteine levels are a risk factor for cardiovascular diseases. This stack helps maintain optimal homocysteine levels, reducing the risk of cardiovascular issues.
  • Support Cognitive and Neurological Health: Methylation is crucial for neurotransmitter synthesis and overall brain function. By supporting methylation, this stack helps maintain cognitive and neurological health.
  • Enhance Detoxification and Antioxidant Activity: Supplements like NAC and CoQ10 support detoxification pathways and reduce oxidative stress, promoting overall cellular health.
  • Improve Energy Production: Supplements like acetyl-L-carnitine and CoQ10 support cellular energy production, enhancing overall vitality and well-being.
  • Support Bone and Muscle Health: Adequate methylation is crucial for maintaining bone and muscle health. This stack supports these processes, promoting overall physical health.

Side Effects/FAQ

Are there any side effects?

While the supplements in the Hypomethylation Entourage Stack Subtype Folate are generally well-tolerated, some individuals may experience mild side effects, particularly when starting a new supplement regimen. Here are some potential side effects to be aware of:

  • Gastrointestinal Discomfort: Some individuals may experience mild gastrointestinal discomfort, such as nausea, bloating, or changes in bowel habits. This is often temporary and can be minimized by starting with lower doses and gradually increasing to the recommended dosage.

  • Allergic Reactions: In rare cases, individuals may have an allergic reaction to one or more of the ingredients in the supplements. Symptoms can include itching, rash, or difficulty breathing. If you experience any of these symptoms, discontinue use and consult your healthcare provider.

Can I take these supplements with my current medications?

It’s essential to consult with your healthcare provider before starting any new supplement regimen, especially if you’re taking medications for cardiovascular or neurological conditions. Some supplements can interact with medications, potentially affecting their efficacy or causing unwanted side effects. Your healthcare provider can help you determine the best approach to integrating these supplements into your current treatment plan.

How long will it take to see results?

The time it takes to see results can vary depending on individual factors such as the severity of hypomethylation, overall health, and adherence to the supplement regimen. Some individuals may notice improvements in their symptoms within a few weeks, while others may take several months to experience significant changes. Consistency is key, so it’s important to take the supplements as directed and maintain a healthy lifestyle to achieve the best results.

Do I need to follow a specific diet while taking these supplements?

While the Hypomethylation Entourage Stack Subtype Folate can help support methylation, it’s essential to follow a healthy diet to achieve the best results. A diet rich in whole foods, including vegetables, fruits, lean proteins, and healthy fats, can help support overall health and improve methylation. Avoiding processed foods, sugary beverages, and excessive refined carbohydrates can also help maintain stable blood sugar levels and support overall health.

Are these supplements safe for long-term use?

The supplements in the Hypomethylation Entourage Stack Subtype Folate are generally considered safe for long-term use when taken as directed. However, it’s important to have regular check-ups with your healthcare provider to monitor your progress and ensure that the supplements continue to meet your needs. Your healthcare provider can also help you determine if any adjustments to your supplement regimen are necessary based on your health status and goals.

By incorporating the Hypomethylation Entourage Stack Subtype Folate into your daily routine, you can support better methylation, improve overall metabolic health, and reduce the risk of associated health issues. This comprehensive approach to managing hypomethylation can help you achieve better long-term health and well-being.

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Glutathione Injections

$175

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