NAD+ Injections & IV Therapy: Benefits, Cost, Dosage & What to Expect
Imagine a therapy that recharges your body’s batteries at the cellular level – a luxurious infusion of vitality that has biohackers, Hollywood celebrities, and wellness enthusiasts buzzing. NAD+ therapy is likened to a high-octane fuel for your cells, powering metabolism and anti-aging processes. In fact, scientists have nicknamed NAD+ the molecule of youth for its pivotal role in cell function and longevity.
The Ultimate Guide to NAD Therapy
In this ultimate guide, we’ll explore NAD injections & IV therapy – covering what NAD+ is, how these treatments work, their benefits, costs, dosage, and exactly what to expect from this cutting-edge wellness trend. Here’s a quick summary:
What is NAD?
NAD+ is a vital coenzyme found in every cell of your body, often considered the fuel of life because it helps convert nutrients into cellular energy. It’s central to metabolism, DNA repair, and healthy aging.
What are NAD injections and IV therapy?
These are treatments that deliver NAD+ directly into your bloodstream or tissues. NAD injections are small shots administered at home and NAD IV drips are slow infusions at a clinic. Both aim to quickly raise your NAD+ levels beyond what oral supplements can achieve
Where do I find NAD+ therapy near me?
NAD+ therapy is offered at many IV lounges, wellness clinics, and through concierge or telehealth services that ship NAD+ injection kits to your home. You can search for “NAD injections near me” for local providers or consider at-home NAD+ programs. (For a full guide, [Read more: NAD injections near me])
How much does NAD therapy cost?
Costs vary widely. A single NAD IV infusion at a clinic can range from $500 to $1,500+ per session, while at-home NAD injection kits average around $300–$400 for a multi-dose vial.
What are the benefits of NAD+ therapy?
Emerging research and patients report benefits like increased energy, enhanced mental clarity, improved mood, anti-aging effects (better skin, slower cellular aging), and even support for addiction recovery.
What are the side effects of NAD therapy?
NAD+ therapy is generally considered safe with a favorable side effect profile. Mild side effects can include nausea or flushing during IV infusions, and injection site irritation for shots. Serious adverse effects are rarely reported.
FAQ about NAD+
Still have questions? In the FAQ section, we address common queries such as the difference between subcutaneous vs intramuscular NAD+ shots, how NAD+ compares to NMN (a popular supplement), recommended injection protocols, and whether NAD+ can ever be harmful. Check out the FAQ for quick answers.
With that overview in mind, let’s dive deeper into each aspect of NAD+ therapy to give you an in-depth understanding of this promising wellness treatment.
What is NAD?
NAD+ is the biochemical bedrock of NAD therapy, so let’s start with the basics.a
What Does NAD+ Mean or Stand For
NAD means nicotinamide adenine dinucleotide, a mouthful that reflects its chemical structure: it’s made of two nucleotides (adenine and nicotinamide) joined through phosphate groups. This coenzyme was first identified over a century ago as a factor essential for cellular respiration. Think of NAD+ as a biochemical “assist” that enables crucial enzymes to function. For example, NAD+ is a required helper for sirtuins and PARPs – enzymes that repair DNA and regulate genes related to aging. Without enough NAD+, these enzymes can’t maintain cellular health, which is why declining NAD+ levels are associated with aging and disease. In fact, NAD levels steadily decline as we age, leaving cells with less energy and repair capacity. Maintaining NAD+ is thus critical for longevity and vitality.
Expert insight: Researchers note that “NAD+ is at the center of cellular metabolism, mitochondrial function, and the biological processes of aging”. In other words, this single molecule influences many pillars of health – from how efficiently your cells produce energy to how well they fix damage and survive stress.
Roles of NAD in Biology
NAD+ plays many roles in biology, functioning almost like a multi-tool for cellular reactions. Key roles include:
- Energy Production: NAD+ is indispensable in converting food into energy. It shuttles electrons in metabolic pathways like glycolysis and the citric acid cycle, ultimately helping generate ATP, the cell’s energy molecule. Without NAD+, your mitochondria (the cell’s power plants) can’t make enough energy, leading to fatigue and organ dysfunction.
- DNA Repair and Cell Longevity: NAD+ is the fuel for enzymes like PARP1 and SIRT1 which repair DNA breaks and regulate genes. Adequate NAD helps these “guardians” keep our genetic material intact and turn on longevity pathways. Low NAD, conversely, is linked to genomic instability and accumulation of DNA damage over time.
- Cell Signaling & Survival: NAD+ is a substrate for signaling molecules. For example, it’s consumed to produce cyclic ADP-ribose, which helps cells respond to calcium signals. NAD+ also activates sirtuins – sometimes dubbed longevity proteins – that adjust metabolism, inflammation, and even our circadian rhythms. Through sirtuins, NAD+ availability can influence processes like inflammation, stress resistance, and cellular aging.
- Metabolic Regulation: As a coenzyme in redox (oxidation-reduction) reactions, NAD+/NADH balances the reactions that break down or build up molecules. It’s intimately involved in fatigue, appetite, and metabolic rate. Fluctuations in NAD can affect how cells handle stress and burn fuel. For instance, NAD+ levels drop in metabolic disorders and boosting NAD+ has shown promise in improving insulin sensitivity and metabolic health in animal studies.
In summary, NAD+ is a workhorse molecule that touches almost every aspect of cell biology. It’s often called the “helper molecule” or even “the anti-aging molecule” for good reason – without NAD+, fundamental life processes grind to a halt. This is why raising NAD+ levels through therapy has such broad potential benefits, as we’ll explore next.
What are NAD+ Injections and NAD IV Therapy?
If NAD+ is the fuel, NAD therapy is the delivery mechanism to top up your tank. NAD injections and NAD IV drips are two methods to introduce NAD+ into your system beyond what you get from diet or oral supplements. Both methods bypass the digestive tract, allowing for higher bioavailability of NAD+. Here’s what they involve:
NAD Injections
NAD+ injections are typically administered with a syringe, delivering the coenzyme into subcutaneous fat or muscle for quick absorption. NAD injections are essentially shots of NAD+ solution, often given either subcutaneously (under the skin) or intramuscularly (into muscle). Each injection delivers a dose of NAD+ directly into your tissues, where it can be absorbed into the bloodstream. Clinics and at-home services offer NAD injections in various doses (common strengths range from 50 mg to 100 mg per shot).
- Subcutaneous vs. Intramuscular: Subcutaneous (SubQ) NAD injections go into the fatty layer (for example, belly fat). Absorption is a bit slower and gentler from fat, and SubQ shots tend to be less painful. Intramuscular (IM) NAD injections go into muscle (often the upper arm or thigh), which has more blood flow, so NAD+ can reach circulation faster. IM injections give a quicker hit of NAD but can be slightly more uncomfortable – comparable to a flu shot in terms of soreness. Many providers let you choose; some at-home NAD programs teach you to self-inject SubQ since it’s very easy and well-tolerated.
- Administration and Convenience: One of the perks of NAD injections is convenience. A quick shot can be done in a clinic or by yourself at home (if prescribed and instructed by a doctor). There’s no lengthy IV line or infusion time. Within 5-15 minutes, it’s done – in fact, some wellness spas offer “NAD+ booster shots” you can get on a lunch break. Because of the small volume, 100% of the NAD+ is absorbed (none lost to digestion), delivering a concentrated dose to your cells.
- How It Feels: Aside from a pinch of the needle, NAD injections are generally well tolerated. Some people report a mild burning sensation at the injection site or a flush if the NAD enters circulation quickly. Injection site irritation can occasionally occur (redness or itch at the spot), but this is usually minor. If irritation happens, rotating injection sites or applying a cool pack/cream can help.
NAD injections are great for those seeking a quick NAD+ boost without spending hours at a clinic. They are often used in anti-aging routines, athletic recovery plans, or general wellness maintenance. (For an in-depth look at how to access injection therapy in your area, [Read more: NAD injections near me]).
NAD+ IV Therapy
NAD IV therapy involves a slow drip of NAD+ directly into your bloodstream, often in a comfortable clinic setting. Each IV bag (like the one shown) may contain 250–1000 mg of NAD+ mixed in saline. NAD IV therapy delivers NAD+ through an intravenous drip, meaning a solution of NAD+ is infused directly into your vein via an IV line. This method allows large doses of NAD+ (500mg or more) to circulate through your body over a controlled period. NAD IV infusions are usually administered in medical spas, wellness clinics, or specialized detox centers under professional supervision.
- Procedure: When you go for NAD IV therapy, a nurse will insert an IV catheter (typically in your arm) and start the NAD+ solution flowing in slowly. Sessions can be lengthy – anywhere from 1.5 to 4+ hours depending on the dose. For instance, a 500 mg NAD+ drip might run ~2–3 hours. The slow drip is crucial; if NAD is infused too rapidly, people can experience discomfort (like chest tightness or lightheadedness). A controlled pace ensures your body tolerates the influx of NAD+ smoothly.
- Clinical Use: NAD IV drips were initially pioneered in addiction treatment centers because of their profound brain restoration effects (more on that in benefits). Now, they are popular in the longevity and wellness scene. A multi-day NAD IV program is not uncommon – for example, some clients undergo a 3- to 10-day course of daily NAD drips for intensive rejuvenation or detox. For milder goals (energy, anti-aging), IV sessions might be done weekly or monthly. Compared to injections, IV drips can deliver higher total amounts of NAD+. The trade-off is the time and expense involved.
- Experience: During a NAD IV, you’ll typically relax in a recliner. You might feel a warmth or flushing sensation as NAD+ enters, or mild nausea if the drip is too fast. Providers often adjust the drip rate if you feel uncomfortable. Many people bring a book or listen to music. Side effects are usually transient (we detail these in the side effects section).
In short, NAD IV therapy is a comprehensive reboot delivered through your veins. It’s ideal if you’re looking for maximal NAD+ replenishment or targeting serious concerns like addiction recovery or chronic fatigue. However, if you just want a quick perk-up, NAD injections might be more your speed.
Where do I find NAD therapy near me?
As NAD therapy’s popularity explodes, it’s becoming widely accessible. If you’re wondering “Where can I get NAD therapy near me?”, you have a few options to explore:
NAD injections near me
Locating NAD injections near you may be as simple as checking local wellness clinics, med spas, or integrative medical practices. Many IV therapy clinics that offer vitamin shots have added NAD+ injections to their menu. To find them, try a web search for “NAD injections [Your City]” or browse the service list of IV drip lounges and anti-aging clinics nearby.
- Wellness Clinics & Med Spas: High-end wellness centers have embraced NAD+ for its anti-aging buzz. You might find NAD injection therapy alongside B12 shots and IV drips at such locations. Some clinics even advertise “NAD+ booster shots” as a quick service.
- Concierge and Telehealth Services: A growing trend is at-home NAD+ injection programs. Companies like enov.one offer telemedicine consultations and ship NAD+ injection kits to your door, complete with vials of NAD+, syringes, and instructions. This allows you to self-administer NAD under medical guidance in the comfort of home. For instance, enov.one’s NAD+ subscription provides a 1000mg NAD vial (about 10–20 doses) starting at $195 per month.
- Integrative/Functional Medicine Doctors: Some physicians, especially those in functional medicine or longevity medicine, incorporate NAD+ into treatment plans.
This is just the tip of the iceberg. Read our article, Find NAD+ Injections Near Me, for a comprehensive list of resources and providers.
NAD IV therapy near me
If you’re seeking NAD IV therapy in your area, you will likely find it at similar establishments as above, with a focus on those equipped for IV infusions:
- IV Drip Clinics: Dedicated IV therapy bars or lounges have sprung up in many cities, and a number of them include NAD+ infusions on their treatment menu.
- Addiction Treatment Centers: NAD IV infusions have a history in addiction detox programs. They sometimes offer multi-day high-dose NAD IV courses to help with withdrawal and brain restoration, under medical supervision.
- Anti-Aging and Biohacking Centers: Longevity clinics and biohacker-focused spas (often found in wellness-forward cities) are also places where NAD IV is offered.
When evaluating NAD IV providers, consider the setting and medical oversight. NAD infusions are safe but can be intense; a reputable clinic will have trained nurses monitoring you. Ask about the dosage and duration of their NAD drips (for example, 250mg over 1 hour vs 750mg over 3 hours) so you know what to expect.
How much does NAD therapy cost?
One of the most common questions is “How much does NAD+ therapy cost?” The answer can vary significantly based on the form (injection vs IV), the provider, and your location. Below we break down typical costs for NAD injections and NAD IV drips, plus considerations on dosage (since cost often scales with dose).
NAD+ injection cost
NAD injection costs can be relatively modest per shot, especially compared to IVs. Here’s what to expect:
- Per Injection Price: In clinic settings, NAD+ intramuscular injections often range from about $25 to $50 per shot for a dose of 50–100 mg. Prices per shot may be higher in urban luxury wellness centers (possibly $50-$100 each). The cost usually includes the NAD solution and the administration by a nurse.
- Packages: Many providers sell NAD injection packages at a slight discount (e.g., a package of 5 or 10 injections). A pack of 4 might be around $129 and 8 for $239 at some spas. Package deals are useful if you plan a series of injections over a month or two.
- At-Home Subscription Kits: Telehealth NAD services bundle multiple doses in one kit. For instance, a monthly NAD+ injection kit (with ~10–20 doses totaling 1000mg) might cost around $300–$400. As mentioned, Enov.One offers a 1000mg NAD+ vial (up to 20 doses) for $375. That breaks down to roughly $18–$37 per dose depending on how you use it, which is quite cost-effective.
Overall, NAD injections are on the more affordable end of NAD therapy. A month’s supply for DIY injections can cost similar to or even less than a single high-dose NAD IV session.
NAD+ injection dosage per day
When considering cost, it’s tied to dosage – how much NAD+ you’re using per day or per injection. Dosage strategies can vary:
- Daily Micro-dosing vs. Larger Doses: Some individuals prefer daily low-dose NAD+ injections, while others do less frequent higher doses. For example, one protocol suggests 5–10 mg of NAD+ daily as a typical prescribed maintenance dose. This is a micro-dose approach aimed at gently sustaining levels. On the other hand, clinics often administer 50mg, 100mg, or even 200mg per injection but on a weekly schedule. Neither is “right” or “wrong” – it depends on your goals and how your body responds.
- Clinical Programs: In addiction or therapeutic programs, patients might receive 100–1000 mg per day via injections or IV in the short term. For example, an intensive protocol might involve 2 weeks of daily 200mg NAD injections for neuroregeneration. These high dosages are usually under medical supervision and aim for acute results (and will cost more due to more NAD used daily).
- Titration: It’s common to start with a lower dose and increase if well tolerated. One anti-aging clinic recommends starting at 20mg NAD+ and gradually ramping up to 100mg per injection, up to 3-5 times per week. This slow titration can help minimize side effects like nausea that sometimes occur with larger NAD spikes.
Given these patterns, your NAD+ usage per day can range from just a few milligrams (if micro-dosing) to a few hundred milligrams (in aggressive therapy). This directly affects cost: 10 mg daily will use only ~300 mg a month, whereas 100 mg weekly uses ~400 mg a month – similar amounts. But if you did 100 mg daily, that’s ~3000 mg a month (3 vials worth!). So, align your dosage with your budget and goals.
Tip: It’s wise to work with a healthcare provider to determine the minimum effective dose for you. Higher doses may give faster or stronger effects but also increase cost and the chance of side effects.
NAD IV therapy cost
NAD IV therapy costs are generally higher than injections due to the larger doses and clinical time required. Here’s an overview:
- Single Session Cost: On average, an NAD+ IV infusion costs $600–$800 per treatment, but can range widely. Some providers charge $500 or less for a low-dose (250mg) IV and $1,000–$1,500 for higher doses (500–1000mg). Generally, $1 per mg of NAD is a benchmark some clinics use – so a 500 mg IV might be around $500..
- Packages and Programs: If you undergo a multi-day NAD IV program, clinics often offer package pricing. For example, a 3-day NAD detox might cost $2,000-$3,000 total. A 10-day intensive can be $5,000+. These packages bundle the costs and sometimes include other therapies (vitamins, coaching, etc.). Some places have membership models where you pay a monthly fee for a certain number of infusions.
- Insurance: NAD therapy is usually not covered by insurance, as it’s considered wellness or experimental for most indications. If you are using it as part of an addiction recovery protocol, occasionally there’s partial coverage under rehab services, but this is the exception rather than the rule. So, assume it’s out-of-pocket.
It’s worth noting that NAD+ IV is a luxury wellness service at this point – priced similarly to high-end spa treatments or elective procedures. The significant cost reflects the powerful effect NAD therapy can have; many clients report it “worth every penny” for the results. However, if cost is a barrier, NAD injections might be solid alternative routes to consider for a NAD boost.
What are the benefits of NAD therapy?
One reason NAD+ therapy has garnered a lot of hype is its sweeping range of potential benefits. From sharper cognition to youthful skin, the list can sound almost too good to be true. Below, we’ll separate the science-backed benefits from the anecdotal ones, and explain how NAD+ might confer each benefit. Remember, while NAD therapy shows promise in many areas, research is still ongoing – we’ll note where the evidence stands.
Nad Injections Benefits
NAD injection benefits largely overlap with NAD’s general benefits, but there are a few unique advantages to the injection route:
- Fast Boost in Cellular Energy: People often feel a surge of energy and reduction in fatigue after a series of NAD injections. By raising NAD+ levels in cells, these shots help your mitochondria crank out more ATP. In one study, NAD supplementation in mice literally improved their running endurance to youthful levels. Users of NAD injections commonly report they “wake up” tired cells, translating to better stamina in daily life. Brain fog lifts, afternoon slumps diminish – it’s like your cells’ low battery mode gets switched off.
- Improved Mental Clarity & Mood: Many NAD injection users say they experience sharper focus, memory, and mood. This makes sense given NAD+ fuels neurotransmitter production and neural cell repair. A research review noted NAD+ therapy may benefit neurodegenerative conditions and even depression. While individual results vary, it’s not uncommon to hear someone after NAD injections remark that they feel more clear-headed and positive. Some biohackers use NAD shots as a nootropic (cognitive enhancer) for this reason.
- Metabolism and Weight Management: NAD+ is integral to metabolic processes, so boosting it can rev up your metabolism. There’s interest in NAD injections for weight loss support – not as a fat-burner per se, but by improving mitochondrial function and insulin sensitivity. Animal studies are encouraging: when older mice received NAD-boosting NMN, they had less age-related weight gain and better insulin sensitivity. Some individuals anecdotally find it easier to shed pounds or maintain a healthy weight with NAD therapy, likely because they have more energy to be active and their cells process nutrients more efficiently. (For deeper analysis of this topic, [Read more: nad injections for weight loss]).
- Convenience & Consistency: A practical “benefit” of NAD+ injections is that it’s easier to keep a consistent routine (compared to scheduling IV drips). Consistency is key for seeing long-term benefits like improved skin or sustained energy. Being able to do a quick shot at home means you’re more likely to stick with the protocol, thus reaping cumulative benefits.
In summary, NAD injections can yield multi-faceted improvements – increased vitality, mental performance, metabolic balance, and more. However, note that benefits often build up over a series of injections; a single NAD shot might give a mild boost, but a course of treatment (say injections over several weeks) is typically recommended to really notice dramatic changes. Always listen to your body and track your results.
NAD IV therapy benefits
NAD IV therapy is considered the heavyweight champion in terms of delivering benefits, due to the high doses possible. Some key benefits associated with NAD IV drips include:
- Deep Detox and Addiction Recovery: One of the most profound uses of NAD IV is in helping people recover from substance addiction. High-dose NAD IV protocols (often 10–15 days of consecutive infusions) have been reported to reduce cravings, alleviate withdrawal symptoms, and restore clarity in individuals detoxing from alcohol, opioids, or other drugs. NAD+ helps repair neural pathways and rebalance neurotransmitters that are disrupted in addiction. Clinics report patients finishing NAD detox feeling like a “fog has lifted” from their brain, with far fewer cravings than they’d normally have. This is a specialized benefit of IV therapy because such high doses (e.g. 750mg/day) are used.
Nurse practitioners in the field note: “The hope is that it helps [patients] feel more naturally calm and be more articulate,” regarding NAD IV’s potential benefits for brain function under stress. - Anti-Aging & Cellular Repair: NAD IV infusions can produce a noticeable “anti-aging” effect systemically. Clients often report improvements in skin tone, hair quality, and joint pain after a round of NAD drips, possibly due to NAD’s role in cellular repair. Research in animals shows restoring NAD+ to youthful levels can reverse aspects of aging – from improved muscle function and endurance to enhanced mitochondrial performance. In humans, early trials of NAD precursors showed trends like lower blood pressure and reduced inflammation markers in older adults. Many longevity doctors consider NAD one of the most promising therapies to slow aging, by replenishing a molecule that declines with age.
- Neurological Benefits: Beyond addiction, NAD IV therapy shows potential for neurodegenerative conditions (like Alzheimer’s, Parkinson’s) and general cognitive enhancement. It may promote neuron repair and protect against neuroinflammation. Some patients with conditions like Parkinson’s have tried NAD IV to improve their energy and focus, with anecdotal success. Even healthy individuals often experience after an IV that their mind feels sharper, mood is lifted, and sleep improves. There’s excitement in the medical community about NAD’s neuroprotective properties; for instance, animal studies found NAD+ infusions helped regenerate retinal cells and improve cognition in Alzheimer’s models.
- Chronic Fatigue & Wellness: NAD IV has been used to combat chronic fatigue syndrome and fibromyalgia with promising results for some. By supercharging cellular energy production and repairing mitochondria, NAD can significantly boost energy levels in those who suffer from debilitating fatigue. Athletes also use NAD IVs for faster recovery from intense training, reporting reduced muscle soreness and a quicker rebound in energy. Some call it an “IV power up.” Over time, NAD+ may also support immune function and resilience (animal studies note benefits to immune function and even lifespan with NAD supplementation.
It’s important to approach these benefits with realistic optimism. While experiences vary, many clients do feel noticeably rejuvenated after NAD IV therapy – “like a decade of weariness was washed away” as one NAD IV user described their before-and-after. The scientific evidence is mounting but not yet conclusive for all these benefits; still, the convergence of research and personal reports is compelling.
For those who still want these benefits but prefer a lower cost alternative, at-home NAD+ shots are the way to go.
NAD Supplement Benefits
In addition to injections and IVs, you might have heard of NAD supplements (like NR – nicotinamide riboside, or NMN – nicotinamide mononucleotide). These are oral supplements that aim to raise NAD+ levels. While this article focuses on injections/IV, it’s worth noting NAD supplement benefits, as they share similar mechanisms:
- General Health and Longevity: NAD+ precursors like NR and NMN have shown promising effects in animal studies: they extend lifespan in mice, improve muscle function, enhance insulin sensitivity, and reduce age-related weight gain. In humans, trials of NR (a form of vitamin B3 that converts to NAD+) have shown it can increase NAD+ levels safely. People take these supplements to support metabolic health, cardiovascular function, and possibly healthy aging. Some small human studies noted improved blood pressure and arterial health in adults taking NR.
- Brain & Mitochondrial Support: NAD+ supplements may help brain health over the long term by providing neurons with more NAD for maintenance. While their effect is milder than an injection (due to lower bioavailability), consistent use of high-quality NAD boosters might improve cognitive function and energy subtly. Users sometimes report better focus, endurance, and sleep after a few weeks on NR/NMN. One registered dietitian noted short-term side effects of NAD supplements are minimal, mostly mild and transient (nausea, flushing, headache) – indicating they are generally well tolerated.
- Skin and Healing: There’s emerging interest in NAD supplements for skin health (some even include NMN in skincare). By aiding DNA repair, NAD+ from within might contribute to better skin cell function and could complement topical NAD+ treatments.
- Ease of Use: The obvious benefit of supplements is convenience – no needles, you just swallow a pill. They’re also far less expensive per dose than injections/IV. For those not ready for injection therapy, taking an NAD+ precursor daily can be a gentle way to support your NAD levels and potentially gain some of the benefits (albeit usually less dramatically than direct NAD therapy).
It’s worth mentioning that not all NAD supplements are equal. Niacin (vitamin B3) is an old-school NAD precursor that can raise NAD+ too, but at high doses it causes flushing. Newer forms like NR (sold in products like Tru Niagen) and NMN are flush-free and potentially more effective at increasing NAD in tissues. Each has its fan base – for example, NMN got famous through Dr. David Sinclair’s research and personal use.
NAD for Looking Younger
Perhaps the most alluring promise of NAD+ therapy is its potential to turn back the clock on aging – or at least slow it down. NAD+ plays a pivotal role in hallmarks of aging, and boosting it can have youthful effects on appearance and vitality:
- Skin Rejuvenation: NAD+ is a darling of the emerging “inside-out” approach to skincare. It supports DNA repair in skin cells and stimulates collagen production, which are key to keeping skin firm and smooth. Dermatologists note that NAD+ may help skin cells fend off UV damage and even prevent certain skin cancers by aiding DNA repair. Dr. Shino Bay Aguilera, a dermatologist, has called NAD+ therapy “medicine for the skin” because of how it promotes cell regeneration. In practical terms, clients who do NAD therapy often notice a healthier glow, improved elasticity, and reduction in fine lines over time. This has led some skincare brands to develop NAD+ Face cream aimed at boosting collagen and moisture. NAD IV or injections plus a topical NAD cream can be a powerful combo for youthful skin.
- Hair and Nails: Though not as thoroughly studied, some individuals report stronger, faster-growing hair and nails after regular NAD therapy. This could be due to improved cellular turnover and protein synthesis in keratinocytes (the cells that make hair and nails) thanks to abundant NAD+.
- Youthful Energy & Vitality: Beyond skin-deep effects, NAD makes people feel younger. It’s not just marketing fluff – one research study found that restoring NAD+ in old mice gave them the muscle strength and endurance of much younger mice. In humans, while we can’t measure “biological age” easily, NAD+ therapy users often experience what could be described as a rollback of age-related issues: better energy, improved eyesight, sharper memory, less joint stiffness, etc. These contribute to an overall more youthful demeanor and capability. Think of a 60-year-old who after NAD treatments starts running 5Ks again and has vibrant skin – that’s the kind of rejuvenation being pursued.
- Cellular Anti-Aging Mechanisms: Scientifically, NAD+ targets aging at the cellular level by activating sirtuins and other pathways. It helps reduce cellular senescence (the accumulation of “old” dysfunctional cells) – in fact, raising NAD+ in aged tissues has been shown to lower the burden of senescent cells in studies. It also improves mitochondrial health and may lengthen telomeres indirectly by supporting genomic stability. All these effects align with longer healthspan (living healthy longer). It’s no surprise NAD+ is often referred to as the anti-aging molecule.
In summary, NAD+ therapy offers a multifaceted approach to looking and feeling younger. It works from the inside to repair and invigorate cells, which translates to external vitality. While it’s not a magical overnight facelift, the cumulative impacts on skin, energy, and health make NAD+ one of the most exciting tools in the longevity and beauty space today.
(For specific strategies on using NAD to maintain a youthful appearance, see [Read more: NAD for looking younger]).
NAD Injections for Weight Loss
Can NAD+ injections aid in weight loss? While they’re not a fat-melting injection in a direct sense, they support many factors that contribute to a healthy weight:
- Boosting Metabolic Rate: NAD+ is intricately involved in metabolism of fats and sugars. Higher NAD+ levels rev up the engines of your metabolism. There’s evidence that animals with boosted NAD burn more energy – for example, mice given NMN had increased energy expenditure and less fat accumulation even without changing diet. People who receive NAD injections often report having more motivation to exercise and less feelings of sluggishness. Over time, this can translate into burning more calories and shedding excess weight, especially when combined with diet and exercise.
- Improved Insulin Sensitivity: NAD+ helps improve how your cells respond to insulin. Better insulin sensitivity means your body is more apt to use glucose for fuel rather than store it as fat. Some overweight individuals have seen improvements in insulin metrics after NAD-boosting therapies, which could help prevent further weight gain and assist weight loss efforts (by reducing insulin resistance, a common hurdle in weight management).
- Reduced Cravings and Appetite Regulation: There’s anecdotal feedback that NAD injections can help stabilize appetite. NAD+ is involved in the hypothalamus and signaling that affects hunger/fullness. Additionally, in addiction treatment, NAD IVs reduced cravings for substances – some of that effect might translate to food cravings. A balanced brain on NAD might be less prone to seek quick dopamine hits from sugary or high-carb foods. This is speculative, but some users indeed notice their sugar cravings diminish when on NAD therapy, making it easier to stick to a healthy diet.
- Muscle Preservation: Losing weight isn’t just about fat loss; preserving lean muscle is key for metabolism. NAD+ aids muscle function and recovery. By keeping your muscle mitochondria healthy, NAD could indirectly support maintaining muscle mass during weight loss, which keeps your resting metabolism higher.
It’s important to set proper expectations: NAD injections are a supportive tool, not a standalone weight loss solution. You won’t magically lose weight unless you also maintain a calorie deficit or exercise regime. However, NAD+ can make those lifestyle changes easier and more effective by energizing you and optimizing your metabolism at the cellular level.
Some clinics even include NAD injections as part of holistic weight loss programs, alongside B12 shots, diet plans, and exercise, to maximize outcomes. If weight management is your goal, consider NAD therapy as one component of a comprehensive plan. Always consult with a healthcare provider for personalized advice.
(For detailed protocols and experiences on this topic, [Read more: nad injections for weight loss]).
NAD+ Injections Before and After
When people talk about NAD+ injections “before and after”, they’re often referring to the noticeable differences in how they feel or function pre- and post- NAD+ therapy. Here’s what to expect:
- Before NAD+ Therapy: Many individuals seeking NAD+ treatment start out with issues like low energy, brain fog, poor concentration, mood lows, or physical fatigue. For instance, you might have been feeling “run down” or not as sharp as you used to. Perhaps workouts leave you overly exhausted or you struggle with recovering from stress. Some have specific “befores” such as suffering from frequent headaches, fitful sleep, or just a sense of accelerated aging (achy joints, dull skin, etc.). On a cellular level, your NAD stores might be suboptimal, especially if you’re older than ~40, as NAD naturally declines with age.
- After a Course of NAD+ Injections: The “after” can be quite remarkable for many. Users commonly report:
- Higher steady energy – no more mid-day crashes, feeling more vibrant upon waking.
- Enhanced mental clarity – thoughts feel organized, memory recall improves, creativity may spark.
- Better mood stability – a sense of calm focus, less anxiety or depressive clouding (some describe it as “the volume of mental chatter turned down”).
- Physical improvements – needing less time to recover from exercise, being able to push harder in workouts, maybe even improved sexual vitality due to better overall energy.
- Appearance – as discussed, subtle changes like brighter skin and eyes, less sallowness or signs of fatigue on the face.
- Higher steady energy – no more mid-day crashes, feeling more vibrant upon waking.
- As one rejuvenation clinic highlights, NAD+ “before and after” can paint a picture of revitalization, with people regaining aspects of their youth – whether it’s playing with grandkids with the energy they had decades ago or regaining the mental sharpness for a demanding job.
- Measurable Changes: While a lot of the benefits are subjective, there can be objective markers too. Some individuals track their biological age or NAD levels via blood tests. For example, intracellular NAD tests can show an increase in NAD levels after therapy. Others notice improvements in bloodwork: e.g., lower inflammatory markers, improved fasting glucose, or normalized blood pressure (if those were issues before). Of course, these changes might also be due to concurrent lifestyle improvements, but NAD+ often plays a facilitating role.
- Cumulative Effects: It’s worth noting that the full before and after impact of NAD+ injections often comes after multiple sessions. One injection might give you a temporary boost for a day or two. However, a series (say 1-2 injections per week for 4-6 weeks) can lead to more sustained transformations. People sometimes don’t realize how much has changed until they reflect a month later – “oh, I haven’t had an afternoon nap in weeks” or “I feel ten years younger!” sort of moments.
For a visual analogy, think of a wilted plant (before NAD) that gets watered and fed (after NAD) – it stands up straighter, leaves perk up, color returns. NAD+ therapy can do that for the human body in a sense, by nourishing your cells.
(For personal testimonials and clinical results, see [Read more: nad+ injections before and after]).
NAD Benefits for Women
Are there specific NAD+ benefits for women? Fundamentally, NAD+ works similarly in all sexes, but there are a few areas where NAD+ therapy might be particularly relevant for women:
- Hormonal Balance and Menopause: Women going through perimenopause or menopause often experience fatigue, brain fog, and metabolic slowdowns partly due to hormonal changes. NAD+ won’t replace estrogen, but by improving cellular energy and brain function, it may alleviate some symptoms.
- Fertility and Reproductive Health: Interestingly, research in animal models has shown NAD+ has implications for ovarian function. A study found that boosting NAD+ levels in older female mice improved egg quality and restored fertility to a degree.
- Mood and Stress Resilience: Statistically, women have higher rates of anxiety and depression in certain life stages. NAD+ is a cofactor in neurotransmitter production (like serotonin, dopamine) and neural energy. NAD therapy has been explored for depression treatment augmentation.
- Skin and Beauty: For women wanting to maintain a youthful complexio, the collagen-boosting, wrinkle-reducing potential of NAD+ (as seen with NAD+ face creams and treatments) is a big draw. Additionally, NAD’s role in hair growth might appeal to women dealing with thinning hair (postpartum or menopausal hair loss).
- Overall Vitality for Busy Lives: Many women juggle careers, motherhood, and more, leading to burnout. NAD+ injections can be a secret weapon to combat burnout by literally recharging the body’s cells.
Whether it’s navigating aging gracefully, preserving fertility options, or simply having the stamina for the myriad demands on women today, NAD+ can provide a supportive boost.
(For women’s health case studies and expert opinions, [Read more: nad benefits for women]).
NAD Skin Care
We’ve hinted at NAD+ and skin throughout, but let’s focus: What does NAD+ do for your skin, and how is it used in skincare?
- Cellular Repair & Anti-Aging: Skin cells are constantly exposed to UV rays, pollution, and other damaging factors that create DNA damage. NAD+ is required for activating PARP enzymes that repair DNA in skin cells.
- Collagen and Elasticity: Collagen is the protein that gives skin its firmness and bounce. Fibroblasts (the cells that produce collagen) slow down as we age, partly due to NAD+ decline. Boosting NAD+ can reinvigorate those cells.
- Moisture and Barrier Function: NAD+ might also improve the skin’s barrier. NAD+-dependent enzymes help form ceramides and other barrier lipids.
- NAD+ in Topical Skincare: Recognizing these benefits, skincare companies have started formulating NAD+ in creams and serums. A 1% NAD+ cream is now available (e.g., Enov.One’s NAD+ Face Cream) which delivers NAD+ to the skin surface. Early studies show applying NAD+ to skin can increase local NAD levels and potentially improve skin quality.
- Glowing “NAD Facial”: Some high-end spas have even experimented with NAD+ in facial treatments, delivering it via microneedling or facial electroporation to get it into deeper layers. These “NAD facials” are said to yield an instant glow and firmness, akin to a light therapy or oxygen facial, but working at the cellular level.
- Healing Skin Conditions: Beyond cosmetics, NAD+ might help certain skin conditions. For instance, psoriasis (a chronic inflammatory skin disease) has been mentioned in NAD research – a pilot study found topical NAD+ analogs helped psoriasis lesions. Also, conditions like eczema might benefit from the barrier-strengthening effects. While not a mainstream treatment yet, it’s a promising area for dermatology research.
NAD+ is poised to become a key player in skincare and dermatology. It operates in the background of skin health – ensuring cells have energy and resilience to renew themselves. By supplementing NAD+ either internally (injections/IV) or externally (creams), you’re addressing skin aging at its root cause, not just masking it.
(For skincare routines and product recommendations involving NAD, [Read more: NAD skin care]).
What are the side effects of NAD therapy?
Any effective therapy can have side effects, and NAD+ is no exception. The good news is that NAD therapy is generally very well tolerated. According to a clinical review, no severe adverse effects have been reported in human trials of NAD+ boosters, suggesting a relatively safe profile.
Most side effects, if they occur, are mild and temporary. They also vary slightly depending on whether you’re doing injections, IV, or supplements. Let’s break it down by category.
NAD Side Effects
General NAD side effects refer to effects of having elevated NAD+ levels or taking NAD precursors internally (like supplements):
- Flushing: High doses of certain NAD precursors (like niacin) can cause a flush – a warmth and redness of the skin (usually face). However, NAD+ injections or NAD itself doesn’t cause a niacin flush. If you’re taking nicotinic acid (a form of B3) you might experience this, but with NR or NMN supplements, flushing is rare.
- Headache: A few people report mild headaches when starting NAD supplementation. This might be due to vasodilation (NAD+ can relax blood vessels slightly). It usually resolves as the body adjusts. Staying hydrated and perhaps lowering the dose can mitigate headaches.
- Fatigue: It sounds ironic since NAD usually boosts energy, but a minority of users feel fatigued or have “flu-like” tiredness for a short period after NAD IV or a large dose. One theory is that as cells ramp up repair processes, the body might temporarily redirect energy to healing, making you feel tired. This is typically short-lived (a day or two) and followed by the positive effects.
- Insomnia or Jitters: On the flip side, if NAD+ is taken late in the day, the energizing effect might cause some insomnia or restlessness at night for sensitive individuals. It’s akin to how some supplements or B vitamins can perk you up. It’s usually mild – maybe trouble falling asleep the night of an infusion if it boosted your alertness too much. To avoid this, plan NAD therapy earlier in the day until you know how it affects your sleep.
The overarching point is that systemic side effects of NAD itself are mild. As a published review concluded: “No study reported severe side effects, supporting the thesis that [NAD interventions] are likely to be relatively safe for human use.” Long-term safety also appears good, as NAD precursors have been used in supplements for years without issue.
NAD Injections Side Effects
For NAD injections (subQ or IM), side effects are minimal and localized:
- Injection Site Reactions: The most common issue is a bit of redness, swelling, or irritation at the injection site. You’re introducing a substance into the tissue, so a mild inflammatory response is normal. Typically, it’s just a small red bump or slight soreness that resolves in a day. Rotating injection sites (abdomen, thigh, arms) can prevent any one area from getting too irritated. If you notice persistent redness or a rash, you might be sensitive to something in the solution – in that case, pause and consult the provider.
- Burning Sensation: Some users feel a slight burning or stinging during the injection as the NAD+ solution disperses, especially with intramuscular shots. This is usually minor and stops after a minute or two. Injecting slowly and ensuring the solution is at room temperature (not cold) helps reduce this sensation.
- Lightheadedness (Rare): Although uncommon, a few people might feel a bit lightheaded or woozy after an IM NAD injection – possibly from a vagal response to the injection rather than the NAD itself. Make sure to be seated or lying when you do the shot if you’re prone to needle vagal responses. The NAD chemical should not cause dizziness at the small doses in injections.
- Infection Risk: As with any injection, using proper sterile technique is crucial. Always use a new sterile needle, clean the skin with alcohol, and follow instructions. The risk of infection or abscess is extremely low when done correctly. If an injection site becomes very painful, warm, and red over days, see a doctor to rule out infection.
Overall, NAD injections are considered very safe and side-effect-light. A majority of people experience no notable side effects aside from perhaps a tiny bit of soreness where the needle went in. The systemic effects (nausea, etc.) that can happen with IVs are rare with the lower doses of injections.
(For an exhaustive list of injection side effects and management tips, [Read more: nad injections side effects]).
NAD supplement side effects
When taking NAD+ boosters orally (NR, NMN, etc.), side effects are minimal, as indicated by clinical trials:
- Digestive Upset: Some people get nausea, indigestion, or diarrhea from NAD precursors, especially if taken on an empty stomach. It’s best to take them with food to avoid GI discomfort. Starting with a lower dose and increasing can also help your system adapt. NMN powder, for example, can cause mild stomach upset in some due to its acidity.
- Flushing or Itching: Niacin (nicotinic acid) can cause flushing and itching at high doses, but nicotinamide (niacinamide) and NR generally do not cause flushing. NR at very high doses (1000mg+) occasionally led to some itching in studies, but no serious flush.
- Headache: As with injections, a small number of people note headaches when they first start NR/NMN. Adequate hydration and dividing the dose (morning and afternoon instead of one large dose) can mitigate this. Headaches were not a common complaint in published research.
- Long-term Safety Questions: No serious side effects have been seen in short-term studies (up to 2-3 months) of NR and NMN. A 2023 study did find extremely high NR levels correlated with an increase in cancer metastasis in mice, but such levels would be hard to reach with normal supplementation. As always, moderation and medical guidance are key.
For the vast majority, NAD supplements cause little to no noticeable side effects. If anything, you might “feel nothing” overtly, which is why some prefer the more immediate kick of injections or IV.
NAD IV Therapy Side Effects
NAD IV therapy, because it delivers a high dose rapidly, has a distinct side effect profile often tied to the infusion rate:
- Nausea and Upset Stomach: This is the #1 side effect of NAD drips. Many people feel a wave of nausea if the IV is flowing too fast. It’s often described as a queasy, “car-sick” feeling in the pit of the stomach. Slowing down the infusion typically relieves the nausea. Clinics will often start the drip slowly and only speed up if you tolerate it well. Having a little food in your stomach before the IV (but not too much) can help prevent queasiness.
- Flushing or Warmth: As NAD goes in, you might experience a warming sensation or flushing of the face. Some people feel their chest or throat get warm. This is generally harmless and subsides after the infusion. It may be related to transient blood vessel dilation or changes in blood flow.
- Chest Pressure or Muscle Tension: At higher infusion speeds, a few individuals report a sense of pressure in the chest or tightness in the muscles (particularly the neck or back of the head). It’s an odd sensation that is again alleviated by slowing or pausing the drip. It’s thought to be related to rapid metabolic changes or calcium flux as NAD floods cells. Not everyone gets this – but if you do, alert the nurse. It will go away once the IV is slowed; taking deep breaths and relaxing helps too.
- Headache or Lightheadedness: During or after an NAD IV, a mild headache can occur. This could be due to the changes in blood flow or blood sugar (some notice a drop in blood sugar with NAD, so having some juice post-IV might be advised). Lightheadedness can happen if you stand up too quickly after the infusion, especially if you were laying down for a couple hours. Make sure to get up slowly and drink water.
- Fatigue or “Wired” Feeling: We noted earlier, some feel fatigued right after as the body is doing repair work; others feel “wired” and energetic. Both are possible. Fatigue usually means you’ll sleep deeply that night and wake up refreshed. Feeling wired means you got a big energy boost – which is fine earlier in the day, but could interfere with sleep if an evening IV.
- Injection Site and Vein Irritation: NAD solutions are a bit acidic, so the vein can feel irritated. Your IV site might be sore or have a bit of redness. In rare cases, the vein can get inflamed (phlebitis). Using a slower drip and a good vein, and flushing with saline after, minimizes this. Make sure the IV is properly placed – if NAD leaks into tissue (infiltration), it can cause local pain and irritation. The nurse will monitor for any swelling at the IV site to avoid this.
- Rare Reactions: Serious allergic reactions to pure NAD+ are very rare (NAD is natural to the body). Clinics are equipped with emergency protocols, but again, this is not typical with NAD – most issues are mild and related to infusion speed.
Patients quickly learn that controlling the drip rate is key to mitigating NAD+ IV therapy side effects. Many actually experience no side effects when the infusion is done slowly enough. It might take longer, but you can essentially avoid the unpleasant symptoms.
Tips to manage NAD IV side effects:
- Start slow (e.g., 50mg per hour rate) and only increase if feeling fine.
- Divide a high dose over two days rather than one marathon session, if needed.
- Stay hydrated and have electrolytes – some clinics add fluids or other vitamins to the NAD bag to buffer side effects.
- Distraction helps: listening to music or meditation can take your mind off any weird sensations.
- Switch from NAD IVs to NAD+ injections, which can be administered at-home for a fraction of the cost.
In summary, NAD therapy’s side effects are manageable and mostly mild. The benefits for most people far outweigh these temporary discomforts. As always, discuss with your healthcare provider to ensure NAD therapy is appropriate for you, especially if you have any medical conditions. With proper supervision, NAD+ can be a safe addition to your wellness regimen.
FAQ about NAD+
Now let’s address some frequently asked questions about NAD+ therapies.
Q: Where do I buy NAD?
A: NAD+ supplements, which are precursors to NAD, are widely available through reputable retailers such as Amaazon. When selecting a direct NAD+ option, you will need to consult a medical professional either via a local clinic or through an online NAD injection telehealth provider like enov.one.
Q: NAD+ subcutaneous vs intramuscular – which is better?
A: What’s the difference between subcutaneous and intramuscular NAD+ injections? – Subcutaneous (SubQ) injections deposit NAD+ into the fat layer under the skin. Intramuscular (IM) injections deliver NAD+ into the muscle tissue. The main differences are in absorption speed and comfort.
Q: NAD Peptide – is NAD+ a peptide?
A: Why do some call NAD+ a peptide and what does that mean? – Chemically, NAD+ is not a peptide. NAD+ is a nucleotide coenzyme (a combination of a vitamin B3 derivative and ATP). Peptides are short chains of amino acids. However, some clinics and wellness literature refer to NAD+ as a “peptide” because they group it with peptide therapies (like injectable anti-aging compounds).
Q: NMN vs NAD – what’s the difference?
A: Is NMN the same as NAD? Should I take NMN or NAD+? – NMN (Nicotinamide Mononucleotide) is a direct precursor to NAD+. Think of NMN as a building block: when you take NMN, your body converts it into NAD+ through a salvage pathway. NAD+ itself, if taken orally, doesn’t survive digestion well – it gets broken down before entering cells. That’s why supplements are typically NR or NMN which can elevate NAD+ internally. If you want to add NAD+ directly, you need either an NAD shot or an IV.
Q: NAD vs NAD+ why the plus, and is there a difference?
A: I see NAD and NAD+ used – are they the same thing? – Yes, when people casually say “NAD” they usually mean NAD+, the oxidized form of nicotinamide adenine dinucleotide. The “+” indicates the molecule is in its oxidized state, ready to accept electrons. Once it picks up electrons, it becomes NADH (the reduced form). In biochemistry, NAD+ and NADH cycle back and forth. But in the context of supplements or therapy, we focus on NAD+ because it’s the form that works as a coenzyme for sirtuins, PARPs, and so on. So, functionally in this article and most discussions, NAD = NAD+.
Q: How often should you get NAD injections?
A: What’s the recommended frequency for NAD+ shots? – It depends on your goals and how you respond. NAD injection protocols are quite flexible. A good approach is to start with a standard protocol (say twice a week) and see. You might find after a month that you feel great and can cut back, or conversely that you want to continue the same frequency. Many users report that in the beginning, the effects of NAD injections are more pronounced, and over time they feel they need it less often to maintain the benefits. This could be due to cells reaching a healthier equilibrium. Always consult with your provider – they may have a specific regimen. For example, some clinics give a series of 6 injections over 3 weeks and then as-needed boosters.
Q: NAD+ subcutaneous injection protocol – what does it look like?
A: a common subcutaneous injection protocol is a loading phase (multiple per week for a few weeks) followed by a maintenance phase (weekly or bi-weekly). Tailoring is common – some may find every other day works best, others once a week suffices. The subcutaneous route’s flexibility is a big advantage.
Q: NAD+ injection dosage per day – how much can I or should I take?
A: What is the ideal NAD+ injection dose per day? – The ideal dose can vary widely. For most people: 5–100 mg per day is a typical range if doing daily injections. It’s best to find the minimum effective dose for you. If 30mg daily makes you feel great, no need to push to 100mg. Higher doses could yield diminishing returns and more cost. Also consider splitting the dose: e.g., 50mg morning and 50mg afternoon rather than 100mg at once, to spread out the NAD boost (though most don’t go to that level of detail).
Q: Can nad be harmful?
A: Are there any dangers or risks to increasing NAD+? – For the average person, NAD+ is very safe and not inherently harmful. Your body naturally uses NAD+ in huge amounts daily. However, there are a few considerations in terms of the quality of NAD you’re using and pre-existing conditions.
Summary
In healthcare, NAD+ is often integrated into personalized treatment plans that may include lifestyle changes and other therapies. While research supports its potential benefits, it’s essential to consult with a healthcare provider before starting NAD+, especially if you’re taking other medications or have underlying health conditions. With its natural origins and supportive role in sleep and mood, NAD+ might be a valuable addition to your overall health improvement strategy.
Supporting Research
Radenkovic, D., Reason, S., & Verdin, E. (2020). Clinical evidence for targeting NAD therapeutically. Pharmaceuticals, 13(9), 247. https://doi.org/10.3390/ph13090247
MDPI Verdin, E. (2015). NAD⁺ in aging, metabolism, and neurodegeneration. Science, 350(6265), 1208–1213. https://doi.org/10.1126/science.aac4854
Covarrubias, A. J., Perrone, R., Grozio, A., & Verdin, E. (2021). NAD⁺ metabolism and its roles in cellular processes during ageing. Nature Reviews Molecular Cell Biology, 22(2), 119–141. https://doi.org/10.1038/s41580-020-00313-x
Cantó, C., Menzies, K. J., & Auwerx, J. (2015). NAD⁺ metabolism and the control of energy homeostasis: A balancing act between mitochondria and the nucleus. Cell Metabolism, 22(1), 31–53. https://doi.org/10.1016/j.cmet.2015.05.023
Conze, D., Brenner, C., & Kruger, C. L. (2019). Safety and metabolism of long-term administration of NIAGEN (nicotinamide riboside chloride) in a randomized, double-blind, placebo-controlled clinical trial of healthy overweight adults. Scientific Reports, 9(1), 9772. https://doi.org/10.1038/s41598-019-46120-z
ResearchGate+1PubMed+1 Poddar, S. K., & Chattopadhyay, A. (2022). The role of NAD⁺ in regenerative medicine. Cells, 11(10), 1637. https://doi.org/10.3390/cells11101637
Dollerup, O. L., Christensen, B., Svart, M., Schmidt, M. S., Sulek, K., Ringgaard, S., Stødkilde-Jørgensen, H., Møller, N., Brenner, C., Treebak, J. T., & Jessen, N. (2018). A randomized placebo-controlled clinical trial of nicotinamide riboside in obese men: Safety, insulin-sensitivity, and lipid-mobilizing effects. The American Journal of Clinical Nutrition, 108(2), 343–353. https://doi.org/10.1093/ajcn/nqy132
PMC+3Københavns Universitets Forskningsportal+3PubMed+3 EatingWell. (2024, October 10). What happens to your body when you take a NAD supplement. EatingWell. https://www.eatingwell.com/what-happens-to-your-body-when-you-take-a-nad-supplement-8719092
EatingWell Kim, M., Lee, J., & Park, H. (2023). Novel approach to skin anti-aging: Boosting pharmacological effects of exogenous nicotinamide adenine dinucleotide (NAD⁺) by synergistic inhibition of CD38 expression. Cells, 13(21), 1799. https://doi.org/10.3390/cells13211799
Bogan, K. L., & Brenner, C. (2008). Nicotinic acid, nicotinamide, and nicotinamide riboside: A molecular evaluation of NAD⁺ precursor vitamins in human nutrition. Annual Review of Nutrition, 28, 115–130. https://doi.org/10.1146/annurev.nutr.28.061807.155443
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