Unless you’re a doctor or biologist, it’s likely that you don’t truly understand everything that goes on within your body. It’s unsurprising really; there’s a lot happening from your toes to the top of your head. So, have you heard of NAD?
NAD+ is a coenzyme that’s vital to help your cells produce energy. When they do that, you feel good about yourself, you’re not falling asleep in your dinner, and you’re able to concentrate on your work. However, studies have shown NAD levels drop by up to 50% by middle age. And do you know what that means? Fatigue, brain fog, headaches, muscle weakness, aging. It’s no fun, right?
The good news is that you can put back what is lost, and there are a few different ways to do that. One option that’s relatively popular is NAD IV. But is it the best choice?
At Enovone, we want to help you choose the best route for your needs. If you don’t have time and excess funds, maybe IV NAD isn’t the right choice for you. But in that case, you can still grab the excellent benefits with our injections, face creams, and nasal sprays. And when you see the NAD before and after pictures, you’ll certainly want to learn more. So, let’s do that now.
Table of Contents
TL;DR
- NAD IV offers 100% bioavailability but cellular uptake remains limited.
- The 2-4 hour time commitment plus treatment costs create a difficult picture for many.
- Repeated high-dose IV exposure triggers CD38 enzyme upregulation, creating biological tolerance that reduces effectiveness.
- Alternative delivery methods like subcutaneous injection achieve excellent results with better convenience.
The Real Science Behind NAD IV Absorption
Before we dig into the whys and wherefores, let’s first define something. What is NAD IV treatment?
If you’ve ever had to have a drip in a hospital before, that’s an IV. It stands for intravenous and it’s simply the way in which the substance you need gets into your bloodstream. Basically, you sit there for a while while a needle goes into a vein, which is then removed and replaced with a catheter. That is attached to a bag of a particular substance, be it fluid for dehydration, or in this case, NAD. Over time, NAD enters your bloodstream in a controlled, steady manner.
To break it down, when you have NAD IV treatment, you have to stay in the clinic or healthcare setting for between two to four hours. It’s also a far more expensive option than administering NAD in other ways, such as subcutaneous injections. At Enovone, we offer these injections and help you get started. Sure, you have to inject yourself, but it’s a lot easier than you think, and once you get used to it, you’ll wonder what you were concerned about.
One reason why we prefer to offer injections over IV NAD is because the IV route isn’t without its challenges. Let’s take a closer look.
The 30-Minute Metabolism Window
When NAD enters your bloodstream, it’s quickly met by CD38 enzymes. The problem with NAD IV is that these enzymes metabolize it extremely quickly, often in between 30 minutes to an hour. It’s a fast breakdown and that means that the very expensive treatment you just paid for has a very short therapeutic window.
Whether you choose NAD IV or at-home treatments, NAD Is a vital supplement for energy and longevity.
Why Your 4-Hour Clinic Sessions Might Be Counterproductive
We mentioned that a NAD drip takes anywhere between two to four hours, and the actual duration varies from person to person. So, not only is it costly in money, but also in time. It’s a big commitment.
Now, that doesn’t mean you shouldn’t do it. If it suits you better, go for it. That’s why it’s vital to weigh the pros and cons and explore other delivery methods. At Enovone, we focus entirely on powerful alternatives like at-home injections, nasal sprays, and face creams that give you control over your wellness journey.
These are ideal if you have a fear of needles or you simply want something that’s effortless to administer.
But back to IV NAD for a second. Check out the table below for a quick peek into how much you can expect a treatment to cost in time and money.
Session Component | Cost Range | Time Investment | Total Investment |
Base NAD IV Treatment | $1,500-$5,000 | 2-4 hours | Base cost |
Travel Time | $0-$200 | 1-2 hours | Opportunity cost |
Recovery/Monitoring | $0-$100 | 0.5-1 hour | Opportunity cost |
Total Per Session | $1,500-$5,300 | 3.5-7 hours | $2,000-$6,000 |
As you can see, when choosing between NAD drip vs at-home administration methods, it’s about more than money. It’s also about the time you lose and what you could be doing with it.
The Annual Commitment Trap
It’s easy to look at time and money spent based on just one treatment, but NAD isn’t a one time deal. You’ll need to have regular treatments to help maintain the effects, and that’s a huge investment over the course of a year.
Think about it – 52 treatments (one per week), so it’s a huge lifestyle disruption. Of course, it also means your bank account takes a big hit.
The Tolerance Problem No One Talks About
Choosing to have IV NAD also means exploring how your body actually responds to it. This is a tricky one because everyone’s different. Yet, there is evidence to suggest that regular high-dose NAD (as in IV treatment) increases CD38 enzyme production.
You might wonder what the problem is. Well, CD38 enzymes degrade NAD pretty quickly. That means that over time, you’re going to need a higher dose to achieve the same benefits you had before. So, you’re getting fewer benefits.
When More NAD+ Actually Hurts
There’s a problem with having a higher dose of NAD over a longer period. That’s because NAD-dependent enzymes like sirtuins become less responsive than before. Again, that cuts down on the long-term benefits you’re paying so much money for through IV NAD.
Behind the Scenes: How NAD IV Clinics Actually Operate
When choosing between NAD IV and other options, it’s useful to understand what actually happens during a treatment.
NAD IV clinics are usually very comfortable, stylish kinds of places – after all, you’re paying for a service. And when you’re sitting there for two to four hours, you need it to be. But what else should you know?
The Regulatory Gray Zone
In-clinic NAD IV treatment sits in a gray area when it comes to regulations. That’s because physicians prescribe compounded NAD+ off-label for wellness purposes. Some of these have different FDA oversight compared to traditional drugs, and that can mean a variation between providers that offer IV treatments.
At Enovone, we’re all about your safety. Our products are FDA approved or compounded medications that are prepared by reputable pharmacies. Once you get in touch with us to enquire about NAD treatment, we ask you to fill in a questionnaire. From that, we determine whether or not you’re suitable for NAD treatment. If you are, we’ll refer you to one of our board-approved doctors who will design a tailored treatment plan for your specific needs.
State-by-State Treatment Lottery
Some states have varying regulations when it comes to IV NAD. Some recognize it as legitimate, others don’t, and that can cause a problem if you happen to be in one of those states. That’s because many states allow broad wellness applications of NAD, but others want a specific medical justification. The result is an inconsistent picture across the country, and it can be confusing if you’re looking to access IV treatment.
For instance, our services are available in all states except for LA and MS. So, while those two are anomalies, 48 out of 50 states isn’t bad!
Revolutionary Alternatives to Traditional IV Treatments
Let’s reiterate a point before we go on. NAD IV isn’t bad. It’s not that at all. It’s just that there are challenges to it, and it’s vital to have all the information to hand first. Yes, you’ll get fast and effective treatment, but the other things that go alongside it do need to be considered too.
So, with that in mind, what are the alternatives?
At-Home Administration Changes Everything
We offer at-home subcutaneous NAD injections that you administer yourself. Now, before you worry about the idea of injecting yourself, it’s extremely easy. And we don’t leave you alone. We offer support every step of the way, and show you exactly how to get started with the injections. Once you’ve done it a few times, it’ll feel like second nature.
You might wonder what subcutaneous actually means. It’s simply the medical term that means injecting the NAD under the surface of the skin. This gives effective uptake and absorption into the bloodstream, while also taking literally seconds to do. Compared to several hours in a clinic, it’s a definite time-saver.
Yes, it’s a slower absorption rate than IV NAD, but that’s not a bad thing. In fact, studies have shown that a slower absorption rate can provide a more sustained cellular response compared to fast NAD IV “spike and crash” patterns.
The other plus point is that you don’t have to travel to a clinic or healthcare setting and sit there for several hours. This is particularly troublesome if you’ve got a lot to do; you can’t really be productive while you’re sitting with an IV.
It’s for all these reasons, and probably several more, why NAD injections are our number one product.
Enovone’s NAD injections are an excellent alternative to NAD IV treatment.
Direct Brain Delivery Through Your Nose
We als mentioned nasal sprays and these are one of the most mysterious, yet surprisingly effective ways to supplement your NAD levels. Starting on our NAD nasal sprays is effortlessly easy; it really couldn’t be anymore simple.
You simply spray one puff in each nostril twice per day. That’s it.
But how does it work? When you spray the product into your nostril it bypasses your first-pass metabolism mechanisms, so it doesn’t get broken down by the liver. Instead, it’s delivered through the olfactory pathway and absorbed directly. Again, it’s a slower absorption than NAD IV, but because it achieves direct brain delivery, it’s ideal if you’re struggling with brain fog. It literally gets to the main issue quickly.
The Microdosing Revolution
When you’re approved for our NAD treatments, one of our board-certified doctors will help identify the best dosage regimen for you. We’re all about the personalized approach, because we know there’s no ‘one size fits all’ route here.
Remember, you should always listen to your doctor and follow their instructions, but in some cases, they may suggest microdosing. This means you take small, frequent NAD dosages, which could lead to better results. The actual timing is aligned with your natural circadian rhythm, helping to keep your body in tune and boosting the quality of your sleep.
Ultimately, it’s about working with your body’s natural rhythms, rather than going against them and causing a wider fluctuation.
Check out the table below for some key information on the different bioavailability percentages and durations of each administration method. It’s clear that IV might have some benefits, but it’s definitely a costly choice compared to other options.
Delivery Method | Bioavailability | Duration | Cost Per Month | Convenience |
IV Clinic | 100% | 2-4 hours | $2,000-$8,000 | Very Low |
Subcutaneous | 70-80% | 5-10 minutes | $400-$800 | High |
Intranasal | 40-60% | 2-3 minutes | $200-$400 | Very High |
Oral Precursors | 15-25% | Instant | $100-$300 | Very High |
Hidden Environmental and Financial Costs
It’s your body, so it’s important to make a decision that suits your needs the best. That includes not only your decision to take NAD supplementation, but also how you’re going to do it. Choosing an NAD drip might suit some people better, and that’s fine. But understanding the hidden environmental and financial costs is key to making an informed choice that takes everything into account.
The Waste Stream You Don't See
When you visit a clinic or healthcare setting for NAD IV treatment, it’s not only about the actual drip itself. Each session actually creates a large amount of medical waste. This includes IV bags, needles, sterile packaging, tubing. Most people are very focused on reducing environmental waste these days – and rightly so. Yet, this large amount of medical waste is problematic in that way.
When you compare that to the minimal amount of waste involved with at-home injections, nasal sprays, and face creams, it’s a big difference.
Carbon Footprint Reality Check
NAD IV involves traveling to a clinic or healthcare setting, the energy used in the facility, and the manufacturing of the actual product itself. All of this creates a large carbon footprint that you just don’t see with regular at-home NAD treatments. In fact, at-home treatments provide a more sustainable solution over the long-term, without detrimentally affecting the planet.
If you’re keen to draw up some comparisons, you’ll find the checklist below very useful.
Checklist: Sustainable NAD+ Treatment Evaluation
- ☐ Calculate total carbon footprint including travel
- ☐ Assess medical waste generation per session
- ☐ Compare home administration options
- ☐ Evaluate reusable vs. single-use components
- ☐ Consider local vs. distant clinic options
- ☐ Review packaging and shipping impacts
- ☐ Assess long-term sustainability of protocol
How Enovone Addresses These Critical Issues
Enovone offers a personalized approach to NAD treatment, and an alternative to NAD IV.
We’ve talked at length about why IV NAD treatment is beneficial but has many challenges that create a solid barrier for many people. Even if you can afford the inflated prices of this treatment, ask yourself whether you really want to invest in it. And do you have the time?
For most people, the answer would be no. But again, it’s a personal choice, so do take the time to weigh up the pros and cons for your specific circumstances.
If you find that you can’t justify the cost of NAD IV, or you simply feel that at-home options will give you more therapeutic benefits, that’s where we come in.
We have the firm belief that everyone should be able to access NAD should they want to. That means no inflated prices, no excessive time constraints, and a safe and effective route forward. Our products are FDA approved or they’re compound medications prepared by highly reputable pharmacies. We also connect you to a board-registered doctor who tailors your treatment to your unique needs. Because let’s be honest, you’re not the same as your neighbor, and they’re not the same as their colleague.
Once you’ve chosen your preferred route, be it injection, face cream, or nasal spray, we don’t simply leave you alone. We’re there for you whenever you need us, whether it’s a quick question or a concern that’s nagging at you.
Ultimately, choosing to improve your health is a step in the right direction. When you choose Enovone, it’s a giant leap towards doing just that!
Final Thoughts
Empowering yourself to boost your energy levels and focus on being your best self is an excellent choice. It means you’re putting yourself and confirming that you truly do matter. Because you do. In a world that’s fast-paced, always shifting, and we have to place a million and one things in front of our own needs, making this decision is a big tick in the right box.
Of course, anything related to your health deserves careful thought and attention. That means choosing the right NAD route for your specific situation. Maybe you’re not a big fan of needles and you can’t overcome your phobia no matter what. That’s fine; it’s not a barrier to NAD treatment. Instead, choose nasal sprays and face creams. Ours are some of the best on the market!
And if you don’t feel that IV NAD is the best option for you, that’s equally fine. In fact, it’s not going to be the best choice for everyone anyway. NAD IV treatment is costly in both money and time, and these are two things that many people simply don’t have a lot of. In that case, our at-home NAD injections will give you excellent results with a lower price tag and less time spent.
Of course, it’s not a magic potion, and it will take time for you to notice major differences, but it will come if you follow your doctor’s guidance. In the meantime, know that putting yourself first means giving yourself a chance to become the very best version of yourself possible.
So, if all this sounds like something you’re keen to have in your life, reach out to us today. Let’s work together to boost your health and give you back your sparkle!
